Registry Code: SCF-RDOS-MH-0001

Classification System: SCF Research Disease & Opportunity System (SCF-RDOS)

Domain: Mental Health & Human Functioning Disorders

REGISTRY STRUCTURE

The SCF-RDOS Mental Health Registry is organized into:

Tier I

Major Psychiatric Disorders

Tier II

Neurodevelopmental Disorders

Tier III

Cognitive Disorders

Tier IV

Behavioral Disorders

Tier V

Trauma & Stress Disorders

Tier VI

Personality Disorders

Tier VII

Substance & Addictive Disorders

Tier VIII

Sleep & Circadian Disorders

Tier IX

Sexual & Gender-Related Conditions

Tier X

Somatic & Psychophysiological Disorders

Tier XI

Impulse-Control Disorders

Tier XII

Attachment & Relational Disorders

Tier XIII

Consciousness & Dissociative Disorders

Tier XIV

Emerging Digital-Era Conditions

Tier XV

Wellbeing Dysfunction Syndromes

TIER I — MAJOR PSYCHIATRIC DISORDERS

Depressive Disorders

1. Major Depressive Disorder
2. Persistent Depressive Disorder (Dysthymia)
3. Treatment-Resistant Depression
4. Recurrent Depressive Disorder
5. Seasonal Affective Disorder
6. Premenstrual Dysphoric Disorder
7. Postpartum Depression
8. Psychotic Depression
9. Melancholic Depression
10. Atypical Depression
11. Double Depression
12. Adjustment-Related Depression

Bipolar Spectrum Disorders

1. Bipolar I Disorder
2. Bipolar II Disorder
3. Cyclothymic Disorder
4. Rapid Cycling Bipolar Disorder
5. Mixed-State Bipolar Disorder
6. Bipolar Disorder with Psychotic Features
7. Substance-Induced Bipolar Disorder

Anxiety Disorders

1. Generalized Anxiety Disorder
2. Panic Disorder
3. Panic Attacks
4. Agoraphobia
5. Social Anxiety Disorder
6. Separation Anxiety Disorder
7. Selective Mutism
8. Illness Anxiety Disorder
9. Anxiety Disorder NOS
10. Performance Anxiety
11. Existential Anxiety

Obsessive-Compulsive Spectrum

1. Obsessive-Compulsive Disorder
2. Body Dysmorphic Disorder
3. Hoarding Disorder
4. Trichotillomania
5. Excoriation Disorder
6. Relationship OCD
7. Religious OCD (Scrupulosity)
8. Harm OCD
9. Contamination OCD

Psychotic Disorders

1. Schizophrenia
2. Schizoaffective Disorder
3. Delusional Disorder
4. Brief Psychotic Disorder
5. Schizophreniform Disorder
6. Shared Psychotic Disorder
7. Substance-Induced Psychosis
8. Psychosis NOS

TIER II — NEURODEVELOPMENTAL DISORDERS

1. Autism Spectrum Disorder
2. Asperger Syndrome (Historical)
3. Attention Deficit Hyperactivity Disorder
4. Attention Deficit Disorder
5. Intellectual Developmental Disorder
6. Global Developmental Delay
7. Specific Learning Disorder
8. Dyslexia
9. Dyscalculia
10. Dysgraphia
11. Language Disorder
12. Speech Sound Disorder
13. Social Communication Disorder
14. Developmental Coordination Disorder
15. Tic Disorders
16. Tourette Syndrome
17. Stereotypic Movement Disorder

TIER III — COGNITIVE DISORDERS

Neurocognitive Disorders

1. Mild Cognitive Impairment
2. Alzheimer Disease
3. Vascular Dementia
4. Frontotemporal Dementia
5. Lewy Body Dementia
6. Mixed Dementia
7. Parkinson Disease Dementia
8. HIV-Associated Neurocognitive Disorder

Cognitive Dysfunction Syndromes

1. Executive Dysfunction
2. Brain Fog Syndrome
3. Cognitive Fatigue Syndrome
4. Processing Speed Deficit
5. Working Memory Impairment
6. Attention Dysregulation
7. Decision-Making Dysfunction
8. Metacognitive Dysfunction
9. Cognitive Rigidity
10. Cognitive Overload Syndrome

TIER IV — BEHAVIORAL DISORDERS

1. Oppositional Defiant Disorder
2. Conduct Disorder
3. Antisocial Behavioral Syndrome
4. Aggression Dysregulation
5. Pathological Lying
6. Compulsive Stealing
7. Habit Disorders
8. Self-Injurious Behavior Disorder
9. Behavioral Dyscontrol Syndrome
10. Chronic Risk-Taking Behavior

TIER V — TRAUMA & STRESS DISORDERS

1. Post-Traumatic Stress Disorder
2. Complex PTSD
3. Acute Stress Disorder
4. Adjustment Disorder
5. Developmental Trauma Disorder
6. Childhood Trauma Syndrome
7. Moral Injury Syndrome
8. Betrayal Trauma Syndrome
9. Combat Stress Reaction
10. Disaster Trauma Syndrome
11. Secondary Traumatic Stress
12. Compassion Fatigue

TIER VI — PERSONALITY DISORDERS

1. Paranoid Personality Disorder
2. Schizoid Personality Disorder
3. Schizotypal Personality Disorder
4. Antisocial Personality Disorder
5. Borderline Personality Disorder
6. Histrionic Personality Disorder
7. Narcissistic Personality Disorder
8. Avoidant Personality Disorder
9. Dependent Personality Disorder
10. Obsessive-Compulsive Personality Disorder
11. Personality Disorder NOS

TIER VII — SUBSTANCE & ADDICTIVE DISORDERS

Substance Use Disorders

1. Alcohol Use Disorder
2. Opioid Use Disorder
3. Stimulant Use Disorder
4. Cannabis Use Disorder
5. Sedative Use Disorder
6. Hallucinogen Use Disorder
7. Nicotine Dependence
8. Inhalant Use Disorder
9. Polysubstance Use Disorder

Behavioral Addictions

1. Gambling Disorder
2. Internet Addiction
3. Gaming Disorder
4. Social Media Addiction
5. Smartphone Addiction
6. Shopping Addiction
7. Work Addiction
8. Exercise Addiction
9. Pornography Addiction
10. Food Addiction

TIER VIII — SLEEP & CIRCADIAN DISORDERS

1. Insomnia Disorder
2. Hypersomnia Disorder
3. Narcolepsy
4. Circadian Rhythm Sleep Disorder
5. Delayed Sleep Phase Syndrome
6. Advanced Sleep Phase Syndrome
7. Shift Work Disorder
8. REM Sleep Behavior Disorder
9. Nightmare Disorder
10. Sleep Terror Disorder
11. Sleepwalking Disorder
12. Sleep Paralysis

TIER IX — SEXUAL & GENDER-RELATED CONDITIONS

1. Gender Dysphoria
2. Sexual Interest/Arousal Disorders
3. Sexual Aversion Disorder
4. Hypersexuality Syndrome
5. Compulsive Sexual Behavior Disorder
6. Paraphilic Disorders
7. Sexual Dysfunction Due to Psychological Factors

TIER X — SOMATIC & PSYCHOPHYSIOLOGICAL DISORDERS

1. Somatic Symptom Disorder
2. Conversion Disorder
3. Functional Neurological Disorder
4. Psychogenic Non-Epileptic Seizures
5. Psychophysiological Insomnia
6. Stress-Induced Pain Syndrome
7. Health Anxiety Syndrome

TIER XI — IMPULSE-CONTROL DISORDERS

1. Intermittent Explosive Disorder
2. Pyromania
3. Kleptomania
4. Compulsive Spending Disorder
5. Impulse Dysregulation Syndrome
6. Compulsive Risk-Taking Disorder

TIER XII — ATTACHMENT & RELATIONAL DISORDERS

1. Reactive Attachment Disorder
2. Disinhibited Social Engagement Disorder
3. Attachment Anxiety Syndrome
4. Attachment Avoidance Syndrome
5. Relational Trauma Disorder
6. Codependency Syndrome
7. Pathological Jealousy
8. Relationship Dependency Disorder

TIER XIII — DISSOCIATIVE & CONSCIOUSNESS DISORDERS

1. Dissociative Identity Disorder
2. Dissociative Amnesia
3. Depersonalization Disorder
4. Derealization Disorder
5. Dissociative Fugue
6. Identity Disturbance Syndrome
7. Persistent Dissociative State

TIER XIV — EMERGING DIGITAL-ERA CONDITIONS

1. Information Overload Syndrome
2. Digital Burnout Syndrome
3. Doomscrolling Disorder
4. Algorithmic Dependency Syndrome
5. Attention Fragmentation Syndrome
6. Virtual Identity Distortion
7. AI Dependency Syndrome
8. Online Social Isolation Syndrome
9. Technostress Disorder

TIER XV — WELLBEING DYSFUNCTION SYNDROMES

Emotional Wellbeing

1. Chronic Loneliness Syndrome
2. Emotional Dysregulation Syndrome
3. Emotional Numbing Syndrome
4. Anhedonia Syndrome
5. Hopelessness Syndrome
6. Meaning Deficit Syndrome
7. Purpose Deficiency Syndrome

Cognitive Wellbeing

1. Burnout Syndrome
2. Occupational Burnout
3. Caregiver Burnout
4. Academic Burnout
5. Executive Burnout

Social Wellbeing

1. Social Isolation Syndrome
2. Social Disconnection Disorder
3. Community Detachment Syndrome
4. Chronic Alienation Syndrome

Existential & Spiritual Wellbeing

1. Existential Distress
2. Spiritual Crisis
3. Identity Crisis
4. Meaning Crisis
5. Moral Distress
6. Moral Exhaustion Syndrome
7. Purpose Collapse Syndrome

Resilience Dysfunction

1. Stress Intolerance Syndrome
2. Adaptation Failure Syndrome
3. Learned Helplessness
4. Chronic Psychological Exhaustion
5. Resilience Deficiency Syndrome
6. Recovery Impairment Syndrome

SCF-RDOS MASTER SUMMARY

Total Registry Categories

15

Total Indications Listed

219

Registry Domains Covered

• Psychiatry
• Clinical Psychology
• Neuropsychology
• Behavioral Medicine
• Addiction Medicine
• Trauma Medicine
• Cognitive Medicine
• Sleep Medicine
• Psychophysiology
• Developmental Disorders
• Personality Disorders
• Digital Health
• Wellbeing Sciences
• Existential Health
• Social Functioning

MASTER DOCUMENT REGISTRY INDEX

SCF-RDOS-MH-0001

SCF-PATH-0001

SCF-VIRAGENESIS-0001

SCF-SEF-MD-0001

SCF-CRD-WORKFLOW-0001

SCF-ENC-SCF-0001

SCF-RDOS-MASTER-0001